姓名:郑永芳
性别:女
职称:副教授
通讯地址:福州市仓山区上三路8号福建师范大学化学与材料学院
邮编:350007
教育经历:
2015/09-2020/07清华大学/中国科学院大学国家纳米科学中心(联合培养),化学,博士
2011/09-2015/-07兰州大学,化学,学士
科研与学术工作经历:
2020/08-至今 福建师范大学 化学与材料学院
研究方向:
1.多肽组装结构的分子机制研究
2.自组装抗菌肽的设计及其性能研究
3.手性生物材料的构建及其应用
科研项目:
1.福建省自然科学基金项目,线性/环状多聚苯丙氨酸自组装纳米结构中手性效应的单分子水平研究, 2021-2024, 在研, 主持
2.福建省教育厅中青年教师教育科研项目,手性对多肽组装结构的调控作用,2021-2022,主持
3.国家自然科学基金委面上项目, 21673055, 多肽组装趋势的分子水平研究, 2017-01-01 至 2020-12-31, 65万元, 结题, 参与
教学情况:
本科生课程:《有机化学》、《无机化学实验》
论文著作:
1.Zheng, Y. F.; Yu, L. L.; Zou, Y. M.; Yang, Y. L. *; Wang, C. *, Steric Dependence of Chirality Effect in Surface-Mediated Peptide Assemblies Identified with Scanning Tunneling Microscopy. Nano. Lett. 2019, 5403-5409.
2.Zheng, Y. F.; Xu, M.; Yu, L. L.; Qu, F. Y.; Lin, Y. C.; Xu, J.; Zou, Y. M.; Yang, Y. L. *; Wang, C. *, Identifying Terminal Assembly Propensity of Amyloidal Peptides by Scanning Tunneling Microscopy. ChemPhysChem 2019, 20 (1), 103-107.
3.Zheng, Y. F.; Fang, X. C.; Yang, Y. L. *; Wang, C. *, Peptide-directed delivery of drug-loaded nanocarriers targeting CD36 overexpressing cells. Colloids and Surfaces A-Physicochemical and Engineering Aspects 2021, 610, 125970.
4.Zheng, Y. F.; Lin, Y. C.; Zou, Y. M.; Yang, Y. L. *; Wang, C. *, Peptide-/protein-mediated nano-bio interface and its applications. Chinese Science Bulletin 2018, 63 (35), 3783-3798.
5. Zheng, Y. F.*; Mao, K. J.; Chen, S. X.; Zhu, H. *, Chirality Effects in Peptide Assembly Structures. Frontiers in Bioengineering and Biotechnology 2021, 9 (517).
6. Zheng, Y. F. *; Luo, W. D; Yu, L. L; Chen, S. X; Mao, K. J; Fang, Q. J; Yang, Y. L; Wang, C; Zhu, H*; Tu, B*; Heterochirality-Mediated Cross-Strand Nested HydrophobicInteraction Effects Manifested in Surface-Bound Peptide Assembly Structures, Journal of PhysicalChemistry B, 2022, 126(3): 723-733.
7.Zheng, Y. F. *; Wu, J. J. *, Overcoming STING Agonists Barriers: Peptide, Protein, and Biomembrane-based Biocompatible Delivery Strategies. Chemistry-an Asian Journal 2022, 17 (6), e202101400.
8.Yu, L. L.; Zheng, Y. F.; Xu, J.; Qu, F. Y.; Lin, Y. C.; Zou, Y. M.; Yang, Y. L. *; Gras, S. L. *; Wang, C. *, Site-specific determination of TTR-related functional peptides by using scanning tunneling microscopy. Nano. Res. 2018, 11 (1), 577-585.
9.Lin, Y. C.; Zheng, Y. F.; Guo, Y. C.; Yang, Y. L.; Li, H. B.; Fang, Y. *; Wang, C. *, Peptide-functionalized carbon dots for sensitive and selective Ca2+ detection. Sensor. Actuat. B: Chem. 2018, 273, 1654-1659.
10.Qu, F. Y.; Yu, L. L.; Xie, H. Y.; Zheng, Y. F.; Xu, J.; Zou, Y.; Yang, Y. L. *; Wang, C. *, Studies on composition and sequence effects in surface-mediated octapeptide assemblies by using scanning tunneling microscopy. J. Phys. Chem. C. 2017, 121 (19), 10364-10369.
11.Zou, Y. M.; Tu, B.; Yu, L. L.; Zheng, Y. F.; Lin, Y. C.; Luo, W. D.; Yang, Y. L. *; Fang, Q. J. *; Wang, C. *, Peptide conformation and oligomerization characteristics of surface-mediated assemblies revealed by molecular dynamics simulations and scanning tunneling microscopy. Rsc Adv. 2019, 9 (70), 41345-41350.
12.Du, H. W.; Hu, X. Y.; Duan, H. Y.; Yu, L. L.; Qu, F. Y.; Huang, Q. X.; Zheng, W. S.; Xie, H. Y.; Peng, J. X.; Tuo, R.; Yu, D.; Lin, Y. C.; Li, W. Z.; Zheng, Y. F.; Fang, X. C.; Zou, Y. M.; Wang, H. Y.; Wang, M. T.; Weiss, P. S. *; Yang, Y. L. *; Wang, C. *, Principles of Inter-Amino-Acid Recognition Revealed by Binding Energies between Homogeneous Oligopeptides. ACS. Cent. Sci. 2019, 5 (1), 97-108.